Gambaran Kadar Glukosa dan Total Kolesterol pada Wanita Hamil di Kabupaten Bangli, Bali
An Overview of Glucose Levels and Total Cholesterol Levels among Pregnant Women in Bangli District, Bali
Keywords:
Diabetes mellitus gestational, glucose levels, total cholesterol levels, pregnancyAbstract
Introduction: Gestational diabetes mellitus (GDM) is a state of glucose intolerance that was first detected during pregnancy. GDM is increasing worldwide, it is estimated that 15% to 22% of all pregnancies are affected by GDM. GDM can be associated with many consequences, such as fetal macrosomia, preeclampsia, and high caesarean rates. The purpose of this study was to determine the description of glucose and total cholesterol levels in pregnant women in Bangli Regency, Bali. Methods: This research method is descriptive by checking glucose and total cholesterol levels using the enzymatic-colorimetric method. The subjects in this study were 33 pregnant women, with sampling method using the probability sampling method, with a simple random sampling technique. Results: The result of this study is, glucose levels in all samples were in the normal category, while for total cholesterol levels 48,48% were in the normal category and 42,42% were in the abnormal category. Conclusion: Normal glucose levels can be caused by several factors such as the age of the respondent under 40 years, gestational age at term, and the hormones that regulate blood glucose in the body functioning properly. An increase in cholesterol levels can be caused by an increase in sexsteroid hormones, as well as changes in liver and adipose tissue metabolism. An increase in total cholesterol levels in pregnant women needs to be watched out for because it can be on of the markers of the incidence of GDM.
ABSTRAK
Pendahuluan: Diabetes melitus gestasional (DMG) merupakan keadaan intoleransi glukosa yang pertama kali terdeteksi selama kehamilan. DMG meningkat di seluruh dunia, diperkirakan 15% sampai 22% dari semua kehamilan dipengaruhi oleh DMG. DMG dapat dikaitkan dengan banyak konsekuensi, seperti makrosomia janin, preeklampsia, dan tingkat operasi caesar yang tinggi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran kadar glukosa sewaktu dan kolesterol total pada ibu hamil di Kabupaten Bangli, Bali. Metode: Metode penelitian ini adalah deskriptif dengan memeriksa kadar glukosa sewaktu dan kolesterol total menggunakan metode enzimatik kolorimetri. Subyek pada penelitain 33 ibu hamil, dengan cara penarikan sampel dengan mengunakan metode probality sampling, dengan teknik simple random sampling. Hasil: Hasil dari penelitian ini, diperoleh kadar glukosa sewaktu seluruh sampel berada pada kategori normal sedangkan untuk kadar kolesterol total sebanyak 48,48% berada pada kategori normal dan 42,42% pada kategori abnormal. Kesimpulan: Kadar glukosa yang normal dapat disebabkan oleh usia repsonden di bawah 40 tahun, usia kehamilan yang cukup bulan, dan hormon pengatur glukosa yang berfungsi dengan baik. Peningkatan kadar kolesterol total dapat disebabkan oleh peningkatan hormon steroid seks, perubahan metabolisme hati dan jaringan adipose. Peningkatan kadar kolesterol total pada ibu hamil perlu diwaspadai karena dapat menjadi salah satu penanda kejadian DMG.
Downloads
References
Adli, F. K. (2021). Diabetes Mellitus Gestasional: Diagnosis dan Faktor Risiko. Jurnal Medika Hutama, 03(01), 1545–1551. https://jurnalmedikahutama.com/index.php/JMH/article/view/312/214
Atiba, A. S., Olofinbiyi, B. A., Akintunde, A. R., Peter, A. O., Clementinah, O. O., & Ibikunle, A. (2017). Maternal Plasma Lipid Profile in Women Screened for Gestational Diabetes Mellitus (GDM). Open Journal of Obstetrics and Gynecology, 07(12), 1209–1215. https://doi.org/10.4236/ojog.2017.712123
Bartels, Ä, Egan, N., Broadhurst, D. I., Khashan, A. S., Joyce, C., Stapleton, M., O’Mullane, J., & O’Donoghue, K. (2012). Maternal serum cholesterol levels are elevated from the 1st trimester of pregnancy: A cross-sectional study. Journal of Obstetrics and Gynaecology, 32(8), 747–752. https://doi.org/10.3109/01443615.2012.714017
Bartels, Änne, & O’Donoghue, K. (2011). Cholesterol in pregnancy: a review of knowns and unknowns. Obstetric Medicine, 4(4), 147–151. https://doi.org/10.1258/om.2011.110003
Dewi, A. M. S., Tiho, M., & Kaligis, S. H. M. (2018). Gambaran Kadar Glukosa Darah Sewaktu Pada Ibu Hamil Trimester III di Rumah Sakit Robret Wolter Mongisidi Manado. Jurnal Medik Dan Rehabilitasi (JMR), 1(2), 1–4. https://ejournal.unsrat.ac.id/index.php/jmr/article/download/22296/21981
Dinas Kesehatan Kabupaten Bangli (2021). Profil Kesehatan Kabupaten Bangli Tahun 2020. [online]. Available at: https://diskes.baliprov.go.id/download/profil-kesehatan-bangli-2020/#.
Direktorat Pencegahan dan Pengendalian Penyakit Tidak Menular-Kementrian Kesehatan R.I. (2017). Wanita dan Diabetes. [online]. Available at: http://p2ptm.kemkes.go.id/wanita-dan-diabetes.
Djamaluddin, N., & Mursalin, V. M. O. (2020). Gambaran Diabetes Melitus Gestasional pada Ibu Hamil di RSUD Prof. Dr. H. Aloei Saboe Kota Gorontalo. Jambura Nursing Journal, 2(1), 124–130. https://ejurnal.ung.ac.id/index.php/jnj/article/view/6858
Garrison, A. (2015). Screening, diagnosis, and management of gestational diabetes mellitus. American Family Physician, 91(7), 460–467. https://pubmed.ncbi.nlm.nih.gov/25884746/
Geurtsen, M. L., van Soest, E. E. L., Voerman, E., Steegers, E. A. P., Jaddoe, V. W. V., & Gaillard, R. (2019). High maternal early-pregnancy blood glucose levels are associated with altered fetal growth and increased risk of adverse birth outcomes. Diabetologia, 62(10), 1880–1890. https://doi.org/10.1007/s00125-019-4957-3
Hossain, M., Rahman, A. K. M. S., Mahjabeen, S., Zaman, M., Abedin, M., Mahmood, T., Razzaque, M. A., & Alam, U. K. (2020). Comparison of Serum Lipid Profile between Gestational Diabetes Mellitus and Pregnant Women with Normal Glucose Tolerance. Journal of Biosciences and Medicines, 08(06), 148–159. https://doi.org/10.4236/jbm.2020.86014
Hu, J., Gillies, C. L., Lin, S., Stewart, Z. A., Melford, S. E., Abrams, K. R., Baker, P. N., Khunti, K., & Tan, B. K. (2021). Association of maternal lipid profile and gestational diabetes mellitus : A systematic review and meta-analysis of 292 studies and 97,880 women. EClinicalMedicine, 34, 1–7. https://doi.org/10.1016/j.eclinm.2021.100830
Li, G., Kong, L., Zhang, L., Fan, L., Su, Y., Rose, J. C., & Zhang, W. (2015). Early Pregnancy Maternal Lipid Profiles and the Risk of Gestational Diabetes Mellitus Stratified for Body Mass Index. Reproductive Sciences, 22(6), 712–717. https://doi.org/10.1177/1933719114557896
Li, Y., Wang, X., Jiang, F., Chen, W., Li, J., & Chen, X. (2021). Serum lipid levels in relation to clinical outcomes in pregnant women with gestational diabetes mellitus: an observational cohort study. Lipids in Health and Disease, 20(1), 4–11. https://doi.org/10.1186/s12944-021-01565-y
Nakrani, M. N., Wineland, R. H., & Anjum, F. (2021). Physiology, Glucose Metabolism. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/pubmed/32809434
Plows, J. F., Stanley, J. L., Baker, P. N., Reynolds, C. M., & Vickers, M. H. (2018). The pathophysiology of gestational diabetes mellitus. International Journal of Molecular Sciences, 19(11), 1–21. https://doi.org/10.3390/ijms19113342
Rahnemaei, F. A., Pakzad, R., Amirian, A., Pakzad, I., & Abdi, F. (2022). Effect of gestational diabetes mellitus on lipid profile: A systematic review and meta-analysis. Open Medicine (Poland), 17(1), 70–86. https://doi.org/10.1515/med-2021-0408
Sobki, S. H., Al-Senaidy, A. M., Al-Shammari, T. A., Inam, S. S., Al-Gwiser, A. A., & Bukhari, S. A. (2004). Impact of gestational diabetes on lipid profiling and indices of oxidative stress in maternal and cord plasma. Saudi Medical Journal, 25(7), 876–880. https://pubmed.ncbi.nlm.nih.gov/15235692/
Ugahari, L. E., Mewo, Y. M., & Kaligis, S. H. M. (2016). Gambaran kadar glukosa darah puasa pada pekerja kantor. Jurnal E-Biomedik, 4(2). https://doi.org/10.35790/ebm.4.2.2016.14616
Vani, D. K. (2015). Alterations in lipid profile in gestational diabetes mellitus (GDM) and type 2 DM women during pregnancy. International Journal of Medical Research and Review, 3(8), 800–804. https://doi.org/10.17511/ijmrr.2015.i8.150
Wang, C., Zhu, W., Wei, Y., Su, R., Feng, H., Lin, L., & Yang, H. (2016). The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index. Journal of Diabetes Research, 2016. https://doi.org/10.1155/2016/3013567
Published
How to Cite
Issue
Section
Copyright (c) 2022 Authors
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with Jurnal Bidan Cerdas agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-SA 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
This work is licensed under a Creative Commons Attribution-Share Alike 4.0 International License
You are free to:
- Share, copy and redistribute the material in any medium or format
- Adapt, remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.