Prevalence and Risk Factor of Hepatitis B among Pregnant Women in Prof. Dr. W. Z. Johannes Hospital Kupang, East Nusa Tenggara, Indonesia

https://doi.org/10.33860/jbc.v5i4.3262

Authors

  • Marni Tangkelangi Departement of Medical Laboratory Technology, Poltekkes Kemenkes Kupang, Kupang, Indonesia https://orcid.org/0000-0003-1823-0966
  • Adrianus Ola Wuan Departement of Medical Laboratory Technology, Poltekkes Kemenkes Kupang, Kupang, Indonesia
  • Yuanita Clara Luhi Rogaleli Departement of Medical Laboratory Technology, Poltekkes Kemenkes Kupang, Kupang, Indonesia

Keywords:

Pregnant Women, Hepatitis B, Risk Factor, Kupang City

Abstract

Introduction: Hepatitis B (HB) during pregnancy was a treating condition for both mother and fetus. Prevalence of Hepatitis B in Indonesia was 0,39 and Kupang City was 0,37 based on Riskesdas in 2018. Purpose: This study aims to measure the prevalence of hepatitis and its risk factors among pregnant women in Prof. Dr. W. Z. Johannes Hospital Kupang. Methods: This study was a descriptive qualitative research using cross sectional design, population was all pregnant women underwent HBsAg Rapid Test excluded HIV co-infection, the sample of this study was 345 pregnant women who visited the hospital during 2021 using constitutive sampling technique, prevalence of hepatitis was calculated and data obtained was analysed using chi-square and fisher exact test for the risk factor. Results: Prevalence of Hepatitis B were 19.7% (66 of 345). Risk factor of hepatitis B on this study was >1 sexual partner (p= 0,000, OR= 53,26), while age (p = 0,597), gestational age (p = 0,597), and parity (p = 0,329) were not the risk factors in this study. Conclusion: Prevalence of Hepatitis B among pregnant women was high, having >1 sexual partner was risk factor of pregnant women in Prof. Dr. W. Z. Johannes Hospital Kupang. It is recommended to encourage early detection and Hepatitis B vaccine on pregnant women to provide specific protection.

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References

ACOG committee. (2013). Committee Opinion No. 561. Obstetrics & Gynecology, 121(4), 911–915. https://doi.org/10.1097/01.AOG.0000428649.57622.a7

Alemu, A. A., Zeleke, L. B., Aynalem, B. Y., & Kassa, G. M. (2020). Hepatitis B Virus Infection and Its Determinants among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis. Infectious Diseases in Obstetrics and Gynecology, 2020, 9418475. https://doi.org/10.1155/2020/9418475

Antuamwine, B. B., Herchel, E. D., & Bawa, E. M. (2022). Comparative prevalence of hepatitis B virus infection among pregnant women accessing free maternal care in a tertiary hospital in Ghana. PLOS ONE, 17(3), e0263651. https://doi.org/10.1371/journal.pone.0263651

Bayo, P., Ochola, E., Oleo, C., & Mwaka, A. D. (2014). High prevalence of hepatitis B virus infection among pregnant women attending antenatal care: a cross-sectional study in two hospitals in northern Uganda. BMJ Open, 4(11), e005889. https://doi.org/10.1136/bmjopen-2014-005889

Bittaye, M., Idoko, P., Ekele, B. A., Obed, S. A., & Nyan, O. (2019). Hepatitis B virus sero-prevalence amongst pregnant women in the Gambia. BMC Infectious Diseases, 19(1), 259. https://doi.org/10.1186/s12879-019-3883-9

Center for Disease Control and Prevention. (2022). Fast Facts on Global Hepatitis B. 2022. https://www.cdc.gov/globalhealth/immunization/diseases/hepatitis-b/data/fast-facts.html

Eba, S., Kejela, G., & Tamiru, A. (2021). Seroprevalence of Hepatitis B Virus and Associated Factors among Pregnant Women Attending Antenatal Care Services at Public Health Facilities in Nekemte Town. International Journal of Reproductive Medicine, 2021, 1–9. https://doi.org/10.1155/2021/9572235

Hasanah Syifa, D. M. (2018). Prevalensi Infeksi Hepatitis B pada Ibu Hamil di Malang. Jurnal Kedokteran Brawijaya, Vol 30, No. 1 (2018), pp.76-80. https://jkb.ub.ac.id/index.php/jkb/article/downloadSuppFile/2046/2776

Indriani, & Anggraini. (2021). Faktor-Faktor Yang Mempengaruhi Kejadian Hepatitis Pada Ibu Hamil. Journal Of Midwirery Science, 1(1), 33–47. https://ojs.ukb.ac.id/index.php/jms/article/view/297

Peraturan Menteri Kesehatan Republik Indonesia Nomor 52 Tahun 2017 Tentang Eliminasi Penularan Human Deficiency Virus, Sifilis Dan Hepatitis B Dari Ibu Ke Anak, 14 450 (2017). Retreived from https://peraturan.bpk.go.id/Details/112155/permenkes-no-52-tahun-2017

Kementerian Kesehatan. (2018). Riset Kesehatan Dasar 2018. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf

Kementerian Kesehatan. (2019). Kementerian Kesehatan Republik Indonesia. Kementerian Kesehatan RI. https://www.kemkes.go.id/article/view/19093000001/penyakit-jantung-penyebab-kematian-terbanyak-ke-2-di-indonesia.html

Kementerian Kesehatan. (2021). Laporan Riskesdas Provinsi NTT 2018. Jakarta: Kementerian Kesehatan. https://repository.badankebijakan.kemkes.go.id/id/eprint/3883/

Kenea, D., & Lemessa, F. (2020). Assessment of Hepatitis B Virus Infection and Associated Factors Among Pregnant Women Attending Antenatal Care Service in Bishoftu Town, South East, Ethiopia. American Journal of Health Research, 8(2), 11. https://doi.org/10.11648/j.ajhr.20200802.12

Khalil, A. S., Hussein, N. R., & Shamdeen, M. Y. (2017). Impact of maternal HBsAg carrier status on pregnancy outcomes in Duhok city, Iraq. Asian Pacific Journal of Tropical Biomedicine, 7(11), 1010–1013. https://doi.org/10.1016/j.apjtb.2017.09.023

MacLachlan, J. H., Locarnini, S., & Cowie, B. C. (2015). Estimating the global prevalence of hepatitis B. The Lancet, 386(10003), 1515–1517. https://doi.org/10.1016/S0140-6736(15)61116-3

Nurhidayati, Afrianty Gobel, F., & Kurnesih, E. (2019). Faktor Risiko Hepatitis B Pada Ibu Hamil Di Kota Makassar Tahun 2019. Journal of Muslim Community Health, 2(3), 22–45. https://pasca-umi.ac.id/index.php/jmch/article/view/536

Pangulu, I. L. H. S. N. (2018). Pemeriksaan Hepatitis B Surface Antigen (Hbsag) dan Anti-Hbs Pada Ibu Hamil. Jurnal Riset Kesehatan, 7(2), 80–84. https://ejournal.poltekkes-smg.ac.id/ojs/index.php/jrk/article/downloadSuppFile/3690/5183

Pither, M., Yusuf, A., & Aziz, R. (2021). Faktor Risiko Kejadian Hepatitis B Pada Ibu Hamil di Kabupaten Luwu Timur: Risk Factors for Hepatitis B Incidence in Pregnant Women in East Luwu District. Media Publikasi Promosi Kesehatan Indonesia (MPPKI), 4(3 SE-Research Article), 432–438. https://doi.org/10.56338/mppki.v4i3.1629

Pratono. (2019). Faktor Risiko Kejadian Hepatitis B pada Ibu hamil di Wilayah DKI Jakarta Tahun 2015 - 2016. Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat, Vol 11 No 2 (2019): Jurnal Kesmas Indonesia, 106–115. http://jos.unsoed.ac.id/index.php/kesmasindo/article/view/1612

Rabiu, K. A., Akinola, O. I., Adewunmi, A. A., Omololu, O. M., & Ojo, T. O. (2010). Risk factors for hepatitis B virus infection among pregnant women in Lagos, Nigeria. Acta Obstetricia et Gynecologica Scandinavica, 89(8), 1024–1028. https://doi.org/10.3109/00016349.2010.482580

Spong, C. Y. (2013). Defining “Term” Pregnancy. JAMA, 309(23), 2445. https://doi.org/10.1001/jama.2013.6235

Tesfu, M. A., Habtemariam, T. T., & Belay, N. B. (2023). Risk factors associated with Hepatitis B virus infection among pregnant women attending public hospitals in Addis Ababa, Ethiopia. PloS One, 18(4), e0284646. https://doi.org/10.1371/journal.pone.0284646

Umare, A., Seyoum, B., Gobena, T., & Haile Mariyam, T. (2016). Hepatitis B Virus Infections and Associated Factors among Pregnant Women Attending Antenatal Care Clinic at Deder Hospital, Eastern Ethiopia. PLOS ONE, 11(11), e0166936. https://doi.org/10.1371/journal.pone.0166936

Wakjira, M., Darega, J., Oljira, H., & Tura, M. R. (2022). Prevalence of hepatitis B virus and its associated factors among pregnant women attending antenatal care in Ambo town, Central Ethiopia: A cross-sectional study. Clinical Epidemiology and Global Health, 15, 101054. https://doi.org/10.1016/j.cegh.2022.101054

Wong, F., Pai, R., Schalkwyk, J. Van, & Yoshida, E. M. (2014). Hepatitis B in pregnancy: a concise review of neonatal vertical transmission and antiviral prophylaxis. Annals of Hepatology, 13(2), 187–195. https://doi.org/10.1016/S1665-2681(19)30881-6

World Health Organization (WHO). (2020). Prevention of mother-to-child transmission of hepatitis B virus (HBV): Guidelines on antiviral prophylaxis in pregnancy (Issue July). https://www.who.int/publications-detail-redirect/978-92-4-000270-8

World Health Organization (WHO). (2022). Hepatitis B. https://www.who.int/news-room/fact-sheets/detail/hepatitis-b

Published

2023-12-31

How to Cite

Tangkelangi, M., Wuan, A. O., & Rogaleli, Y. C. L. (2023). Prevalence and Risk Factor of Hepatitis B among Pregnant Women in Prof. Dr. W. Z. Johannes Hospital Kupang, East Nusa Tenggara, Indonesia. Jurnal Bidan Cerdas, 5(4), 220–226. https://doi.org/10.33860/jbc.v5i4.3262

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