Relationship between Side Effects of Anti-tuberculosis Drugs (ATDs) and Adherence to Medication in Elderly Patients with Tuberculosis
Keywords:
Drug Side Effects, Anti-Tuberculosis Drugs (ATDS), Medications Adherence, Elderly PeopleAbstract
One of the obstacles to the treatment of tuberculosis (TB) patients is the side
effects of anti-tuberculosis drugs (ATDs) which cause patients to be reluctant to continue the medication. The elderly experience various physical and physiological changes in the body
system, including susceptibility to drug side effects, decreased knowledge and memory,
resulting in non-compliance with taking the medication. This study aims to determine the
relationship between ATDs side effects and compliance with taking medication for elderly
patients at the Tanjung Selor Health Center, Bulungan Regency, North Kalimantan Province.
This study used a quantitative cross-sectional approach. The sample was taken by total
population, namely elderly tuberculosis patients undergoing tuberculosis treatment as many as
30 respondents. The research instrument was a questionnaire of drug side effects and ATDs
compliance. Statistical test used Fisher's Exact. The results showed that most patients (76.7%)
complained of OAT side effects and the rest without OAT side effects (23.3%). Treatment
compliance was 20% compliant, and 80% were non-compliant. Fisher's Exact statistical test
obtained p-value = 0.016 (< α = 0.05). It was concluded that there was a significant relationship between OAT side effects and treatment compliance in elderly patients with tuberculosis. Recommendations for health workers to give special attention to elderly patients with medication monitoring and compliance motivation. Future researchers should identify the involvement of family and health workers to monitor the side effects of anti-tuberculosis drugs.
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