Uji Efikasi Kapsul Pare-Primakuin dan DHP-Primakuin serta Pengaruhnya terhadap Kualitas Hidup Pasien Malaria Falsiparum Tanpa Komplikasi di RSUD Manokwari Tahun 2019
Keywords:
effective, gametocytes, hemoglobin, instruments, parasitesAbstract
Penelitian ini bertujuan untuk menganalisis efek terapi kombinasi obat antimalaria terhadap kualitas hidup pasien malaria falsiparum. Penelitian ini merupakan penelitian eksperimental murni (true-experimental). Jumlah sampel sebanyak 134 pasien penderita malaria di RSUD manokwari. Variable penelitian meliputi karakteristik responden, suhu aksila, hemoglobin, Gametosit (/µL darah), gejala klinis responden, Jumlah Parasit Aseksual dan Gametosit, dan Kualitas Hidup SF-36. Analisis data yang digunakan adalah uji che-square dan uji Mann Whitney. Hasil penelitian yaitu Pengobatan kapsul pare-primakuin mempunyai efikasi terhadap malaria falsiparum tanpa komplikasi dengan nilai ITT sebesar 92% dan PP sebesar 100%. Kualitas hidup pasien malaria falsiparum tanpa komplikasi pada pengobatan DHP-P lebih tinggi dibandingkan dengan KP-P yang ditinjau dari 8 domain yaitu: fungsi fisik, peran fisik, nyeri tubuh, kesadaran secara umum, vitalitas, sungsi sosial, peran emosional dan kesehatan mental. Kesimpulan yaitu Pengobatan DHP-primakuin lebih efektif dibandingkan dengan kapsul pare-primakuin dengan nilai ITT sebesar 96% dan PP sebesar 100%.
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