Original Articles
Open Access

Determinants of The Incidence of Multidrugs Resistant Tuberculosis (MDR TB) In North Luwuk District

Determinan Kejadian Multidrugs ResistenTuberculosis (MDR TB) di Kecamatan Luwuk Utara

Sukmawati Sukmawati 1 ID , Nitro Galenso 2 ID
1 Poltekkes palu
2 Poltekkes kemenkes palu
Published 2021-04-30
Vol. 1 No. 2 (2021) Pages 52-58
DOI https://doi.org/10.33860/lnj.v1i2.1885
Views / Downloads 712 402
Download PDF

Abstract

Indonesia termasuk high burden countries, artinya Indonesia memiliki permasalahan besar menghadapi TB. Penelitian bertujuan mengidentifikasi Karakteristik Penderita dan determinan  MDR-TB di wilayah Kecamatan Luwuk Utara. Jenis Penelitian Case control study. Teknik sampel dengan total sampling. Analisis data dengan Odds Ratio untuk mengetahui besar peluang variabel beresiko terhadap kejadian kasus MDR-TB.  Odds Ratio dengan 95% confidence interval diperoleh bahwa PMO, Dukungan Keluarga, dan Keteraturan Minum Obat adalah 100% sehingga tidak dilanjutkan untuk melihat besarnya peluang beresiko. Pengetahuan merupakan determinan MDR TB dengan nilai OR >0,1. Analisis variabel akses pelayanan menunjukkan nilai OR>1,75 artinya variabel akses pelayanan Kesehatan pada responden memiliki peluang 1,75 lebih besar menderita MDR TD. Penyuluhan Kesehatan diperoleh nilai OR>11 jadi 11,5 lebih berpeluang memiliki risiko MDR-TB. Hasil analisis variabel petugas Kesehatan menunjukkan nilai OR>5,8. Artinya peluang berisiko variabel petugas Kesehatan adalah 5,8 lebih besar menderita MDR-TB. Kesimpulan penelitian adalah Karakteristik MDR TB tertinggi pada usia 17-25 tahun dan 46-55 tahun, jenis kelamin laki-laki, Pendidikan SLTA dan pekerjaan wiraswasta. Hasil analisis Odds Ratio menunjukkan bahwa yang bermakna adalah variabel pengetahuan dimana OR>0,1.

Keywords: MDR TB Kasus Kontrol Determinan

How to Cite

Determinants of The Incidence of Multidrugs Resistant Tuberculosis (MDR TB) In North Luwuk District : Determinan Kejadian Multidrugs ResistenTuberculosis (MDR TB) di Kecamatan Luwuk Utara. (2021). Lentora Nursing Journal, 1(2), 52-58. https://doi.org/10.33860/lnj.v1i2.1885
More Citation Formats

Views / Downloads

No statistics available yet.
712 Abstract
402 Downloads

Files

PDF
0 downloads Download

License

Copyright (c) 2022 Sukmawati Sukmawati, Nitro Galenso

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

References

Dasar Tahun 2018. Kementrian Kesehat RI. 2018;53:1689–99.

Khan MS, Hutchison C, Coker RJ. Risk factors that may be driving the emergence of drug resistance in tuberculosis patients treated in Yangon, Myanmar. PLoS One. 2017;12:1–10.

Baya B, Achenbach CJ, Kone B, Toloba Y, Dabitao DK, Diarra B, et al. Clinical risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in Mali. Int J Infect Dis [Internet]. 2019;81:149–55. Available from: https://doi.org/10.1016/j.ijid.2019.02.004

Rajendran M, Zaki RA, Aghamohammadi N. Contributing risk factors towards the prevalence of multidrug-resistant tuberculosis in Malaysia: A systematic review. Tuberculosis [Internet]. 2020;122:101925. Available from: https://doi.org/10.1016/j.tube.2020.101925

Pradipta IS, Forsman LD, Bruchfeld J, Hak E, Alffenaar JW. Risk factors of multidrug-resistant tuberculosis: A global systematic review and meta-analysis [Internet]. Vol. 77, Journal of Infection. Elsevier Ltd; 2018. 469–478 p. Available from: https://doi.org/10.1016/j.jinf.2018.10.004

Montes K, Atluri H, Silvestre Tuch H, Ramirez L, Paiz J, Hesse Lopez A, et al. Risk factors for mortality and multidrug resistance in pulmonary tuberculosis in Guatemala: A retrospective analysis of mandatory reporting. J Clin Tuberc Other Mycobact Dis [Internet]. 2021;25:100287. Available from: https://doi.org/10.1016/j.jctube.2021.100287

Chung-Delgado K, Guillen-Bravo S, Revilla-Montag A, Bernabe-Ortiz A. Mortality among MDR-TB cases: Comparison with drug-susceptible tuberculosis and associated factors. PLoS One. 2015;10:1–10.

Horter S, Stringer B, Greig J, Amangeldiev A, Tillashaikhov MN, Parpieva N, et al. Where there is hope: A qualitative study examining patients’ adherence to multi-drug resistant tuberculosis treatment in Karakalpakstan, Uzbekistan. BMC Infect Dis [Internet]. 2016;16:1–15. Available from: http://dx.doi.org/10.1186/s12879-016-1723-8

Deshmukh RD, Dhande DJ, Sachdeva KS, Sreenivas AN, Kumar AMV, Parmar M. Social support a key factor for adherence to multidrug-resistant tuberculosis treatment. Indian J Tuberc [Internet]. 2018;65:41–7. Available from: http://dx.doi.org/10.1016/j.ijtb.2017.05.003

Skinner D, Claassens M. It’s complicated: Why do tuberculosis patients not initiate or stay adherent to treatment? A qualitative study from South Africa. BMC Infect Dis [Internet]. 2016;16:1–9. Available from: http://dx.doi.org/10.1186/s12879-016-2054-5

Chen B, He T. Social support received by multidrug-resistant tuberculosis patients and related factors : a cross- sectional study in Zhejiang Province , People ’ s Republic of China. 2016;1063–70.

Stringer B, Lowton K, Tillashaikhov M, Parpieva N, Ulmasova D, Cros P, et al. ‘ They prefer hidden treatment ’: anti-tuberculosis drug-taking practices and drug regulation in Karakalpakstan. 2016;20:1084–90.

Similar Articles

Similar Articles

You may also start an advanced similarity search for this article.